Mr. Frances Hocutt

frances.hocutt@gmail.com
github.com/fhocutt

Education

  • University of Washington MS, Chemistry
  • University of Washington MS, Materials Science and Engineering
  • Harvey Mudd College BS with distinction, Chemistry

Skills

  • Languages: Python, PHP. Some Java, Javascript, Perl.
  • Databases: SQL, MySQL, SQLite.
  • Software/Tools: Git, Github, Vagrant, MediaWiki, jQuery, Phabricator, Gerrit.

Programming Experience

Projects

  • Provided easy API to access Page Assessment information in a usable and generic way on Wikipedia. Tech used: PHP, MySQL.
  • UX improvements to the Secure Polling extension. Tech used: PHP, jQuery.
  • Created a recommendation system to drive participation in the Wikimedia Grants program’s IdeaLab and to connect participants with projects and resources. (Inspire Grants: Gender gap campaign) Tech used: Python, MediaWiki, MySQL.
  • Created a recommendation system to facilitate mentorship in the Wikipedia Co-op learning space, and to make it possible to track participants’ learning and editing outcomes. (Reimagining Wikipedia Mentorship; code repository.) Tech used: Python, MySQL, MediaWiki.
  • Contributions to Dreamwidth (Perl), Java Wiki Bot Framework (Java), mwclient (Python).

Leadership Experience

Workshops/Trainings

Conference Presentations

Publications

  • “When ‘I Didn’t Mean To’ Makes it Worse”. Model View Culture, April 2014.
  • “I Didn’t Want To Lean Out”. Model View Culture, February 2014.
  • Barcenas, M.; Chennameneni, N. K.; Wolfe, B.; Hocutt, F.; Gelb, M.; Turecek, F.; Scott, C. R. Newborn screening of mucopolysaccharidosis II (Hunter syndrome) and VI (Maroteaux-Lamy syndrome) using flow injection tandem mass spectrometry and newly developed reagents. Mol. Genetics and Metabolism, 2014, 111 (2), S23.
  • Venkatesan, H.; Hocutt, F. M.; Jones, T. K.; Rabinowitz, M. H. A One-Step Synthesis of 2,4-Unsubstituted Quinoline-3-carboxylic Acid Esters from o-Nitrobenzaldehydes. J. Org. Chem., 2010, 75 (10), pp 3488–3491.
  • Rosen, M. D.; Venkatesan, H.; Peltier, H. M.; Bembenek, S. D.; Kanelakis, K. C.; Zhao, L. X.; Leonard, B. E.; Hocutt, F. M.; Wu, X.; Palomino, H. L.; Brondstetter, T. I.; Haugh, P. V.; Cagnon, L.; Yan, W.; Liotta, L. A.; Young, A.; Mirzadegan, T.; Shankley, N. P.; Barrett, T. D.; Rabinowitz, M. H. Benzimidazole-2-pyrazole HIF Prolyl 4-Hydroxylase Inhibitors as Oral Erythropoietin Secretagogues. ACS Med. Chem. Lett., 2010, 1 (9), pp 526–529.

Patents

  • Gelb, M. H.; Kumar, A. B.; Hocutt, F.; Spacil, Z.; Barcenas Rodriguez, M. N.; Turecek, F.; Scott, C. R. (University of Washington, USA). Reagents and methods for screening MPS I, II, IIIa, IIIb, IVa, VI, and VII. US Pat. Appl. 2014054398, September 5, 2014.
  • Bembenek, S. D.; Hocutt, F. M.; Leonard, B. E.; Rabinowitz, M. H.; Rosen, M. D.; Tarantino, K. T.; Venkatesan, H. (Janssen Pharmaceutica NV, Belg.). Quinazolinones as prolyl hydroxylase inhibitors. US Pat. Appl. 20100204226, August 12, 2010.
  • Hocutt, F. M.; Leonard, B. E.; Peltier, H. M.; Phuong, V. K.; Rabinowitz, M. H.; Rosen, M. D.; Tarantino, K. T.; Venkatesan, H.; Zhao, L. X. (Janssen Pharmaceutica NV, Belg.). Benzoimidazoles as prolyl hydroxylase inhibitors. PCT Int. Appl. WO 2009134750, November 5, 2009.
  • Rosen, M. D.; Rabinowitz, M. H.; Zhao, L. X.; Hocutt, F. M. (Janssen Pharmaceutica NV, Belg.). Benzoimidazole glycinamides as prolyl hydroxylase inhibitors. PCT Int. Appl. WO 2009134754, November 5, 2009.

Research Experience

  • Department of Chemistry, University of Washington, Seattle, WA. Winter 2012-Spring 2013. Developed diagnostic assays to enable the detection of Krabbe disease and mucopolysaccharidosis in newborns. Designed and synthesized enzyme substrates for use in multiplex mass-spectrometric enzyme assays, iteratively guided substrate solubility and efficacy in assay. Analysis and characterization involved analytical UHPLC/MS, NMR, MS, and HPLC.
  • Department of Materials Science and Engineering, University of Washington, Seattle, WA. Winter 2011-Fall 2011. Synthesized nanostructures and trapped these using optical dielectrophoresis. Numerically modeled forces on trapped particles using Python. Developed a new, high-volume solution-phase synthesis of Pd nanowires. Characterized nanowires by SEM, TEM, STXM, UV-vis spectroscopy, and XRD. As one of the lab’s first two graduate students, set up the general chemistry areas and project-related portions of the lab.
  • Johnson & Johnson Pharmaceutical Research and Development, La Jolla, CA. Research Associate, 9/09 to 5/10; Research Assistant, 6/07 to 9/09. Prepared, purified, and characterized novel compounds for biological testing on scales up to 20 g. Developed new synthetic methodologies and optimized existing ones. Primary characterization methods included HPLC, LC/MS, NMR. Inventor on three patents (US2010/0204226, PCT Int. Appl. WO 2009134750, PCT Int. Appl. WO 2009134754).
  • Chemistry Department, Harvey Mudd College, Claremont, CA. Thesis research, 9/06–5/07. Worked to develop a streamlined synthesis of the endiandric acids.
  • Chemistry Department, University of Virginia, Charlottesville, VA. NSF-REU, Summer 2006. Explored options for the synthesis of a new combinatorial library scaffold. Attempted systematic optimization of a N-fluorination reaction. Prepared a range of intermediates in the synthesis of lonidamine derivatives. Reaction monitoring by MS; characterization with MS, NMR.

Teaching Experience

  • Teaching Assistant, University of Washington, Seattle, WA. Fall 2012. Taught quiz sections for introductory organic chemistry for undergraduates (CHEM 237).
  • Teaching Assistant, University of Washington, Seattle, WA. Winter 2012. Taught lab sections for the undergraduate introductory organic chemistry lab (CHEM 241).
  • Teaching Assistant, University of Washington, Seattle, WA. Fall 2010, Spring 2011, Fall 2011. Taught the lab portion of the introductory undergraduate materials science and engineering class (MSE 170).
  • Curriculum development, Chemistry Department, Harvey Mudd College, Claremont, CA. NSF-REU, Summer 2005. Designed, tested, and optimized experiments involving computer-controlled data collection for the general chemistry laboratory class. Documented procedures and prepared equipment.
  • Grader/Tutor, Chemistry Department, Harvey Mudd College, Claremont, CA. 9/04–5/07. Tutored students in organic and general chemistry. Evaluated coursework for organic and general chemistry.

Awards & Fellowships

  • ARCS Fellow (2010)
  • American Chemical Society, Division of Analytical Chemistry Award (2007)
  • Dean’s List (’03–’04; ’05–’06)
  • Bronze Medal at the International Chemistry Olympiad (Greece, 2003)
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